surmount-5 tirzepatide vs semaglutide head-to-head weight loss nejm 2024 Tirzepatide vs Semaglutide for Obesity – NEJM, May 2025 Relevant to endocrinology, internal medicine, cardiology, obesity medicine • Tirzepatide: −20.2% weight loss at 72 wks • Semaglutide: −13.7% • Greater waist reduction
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